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Brand name: metformin
Generic name: glucophage, Metformin, Glucophage, Diabex, Diaformin, Fortamet, Riomet, Glumetza, metfornin, metforrnin
metformin description:
MANAGEMENT: Close monitoring for the development of hypoglycemia is recommended if ACE inhibitors are coadministered with metformin, particularly in patients with advanced age and/or renal impairment. Published clinical information exists for the use of other sulfonylureas including glyburide, glipizide, chlorpropamide, and tolbutamide in combination with metformin. The active comparator metformin (n=137) was administered at 500 mg twice daily initially and titrated up to 1000 mg twice daily (mean last dose 1365 mg). In patients where monotherapy with Amaryl or metformin has not produced adequate glycemic control, the combination of Amaryl and metformin may have a synergistic effect, since both agents act to improve glucose tolerance by different primary mechanisms of action. Metformin and rosiglitazone should be used carefully as age increases and older adults may need a lower dose of metformin and rosiglitazone.
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